PUBLICATIONS

Gautam, P., Jaiswal, A., Aittokallio, T,, Al-Ali, H., and Wennerberg, K. 2019. Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets. Cell Chemical Biology pii: S2451-9456(19)30107-2.

Strang, B. L., C. R. M. Asquith, H. F. Moshrif, C. M.-K. Ho, W. J. Zuercher, and H. Al-Ali. 2018. Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data. PLOS ONE 13:e0201321.

Al-Ali, H., Y. Ding, T. Slepak, W. Wu, Y. Sun, Y. Martinez, X.-M. Xu, V. P. Lemmon, and J. L. Bixby. 2017b. The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury. The Journal of Neuroscience 37:7079–7095.

Swords, R. T., D. Azzam, H. Al-Ali, I. Lohse, C.-H. Volmar, J. M. Watts, A. Perez, A. Rodriguez, F. Vargas, R. Elias, F. Vega, A. Zelent, S. P. Brothers, T. Abbasi, J. Trent, S. Rangwala, Y. Deutsch, E. Conneally, L. Drusbosky, C. R. Cogle, and C. Wahlestedt. 2017. Ex-vivo Sensitivity Profiling to Guide Clinical Decision Making in Acute Myeloid Leukemia: A Pilot Study. Leukemia Research.

Al-Ali, H., H. Gao, C. Dalby-Hansen, V. A. Peters, Y. Shi, and R. Brambilla. 2017. High content analysis of phagocytic activity and cell morphology with PuntoMorph. Journal of Neuroscience Methods 291:43–50.

Al-Ali, H. 2016. The evolution of drug discovery: from phenotypes to targets, and back. Med. Chem. Commun. 7:788–798.

Al-Ali, H., D. H. Lee, M. C. Danzi, H. Nassif, P. Gautam, K. Wennerberg, B. Zuercher, D. H. Drewry, J. K. Lee, V. P. Lemmon, and J. L. Bixby. 2015. Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets to Promote Axon Growth. ACS Chemical Biology 10:1939–1951.​

 

Al-Ali, H., S. C. Schürer, V. P. Lemmon, and J. L. Bixby. 2013. Chemical interrogation of the neuronal kinome using a primary cell-based screening assay. ACS chemical biology 8:1027–36.